What is mesotherapy?

Mesotherapy is a cosmetic procedure that does not require surgery and is performed by injecting various bioactive substances (vitamins, minerals, amino acids, peptides, antioxidants, stem cell extracts, etc.) under the skin. This procedure is performed to provide rejuvenation and renewal in the skin. Mesotherapy affects the cells in the skin with the microinjection method and helps to regain the healthy appearance of the skin.
Mesotherapy applications aim to reverse the signs of aging in the skin. The aging process is associated with the deterioration of the functions of fibroblast cells in the skin. Fibroblasts are the cells responsible for the production of structural components in the skin. The functions of these cells decrease with age, which causes the skin to sag and wrinkles to form. Mesotherapy aims to increase collagen production and rejuvenate the skin by supporting these fibroblasts.
Various mesotherapy mixtures provide the bioactive substances that aging skin needs. These substances help to increase the function of fibroblasts and to provide rejuvenation of the skin. Such mixtures contain components such as amino acids, nucleosides, vitamins and minerals. In addition, antioxidants and moisturizing substances that reduce oxidative stress in the skin are also used.
The main purpose of mesotherapy is to stimulate the cells under the skin, accelerate the skin's natural renewal process and eliminate the signs of aging on the skin. This process is a popular method with a fast recovery time and minimal side effects.

Mesotherapy treatments used in skin rejuvenation
Mesotherapy treatments used for skin rejuvenation are called biorevitalization and biolifting depending on the products used. Components that support skin health such as vitamins, amino acids, minerals, coenzymes and antioxidants are widely used in mesotherapy treatments.
Vitamins and Vitamin-like Substances: Antioxidants such as vitamin C, vitamin A, and vitamin E play an important role in the skin's aging process. While vitamin C supports collagen synthesis, vitamin A ensures the renewal of the epidermis. Vitamin E helps repair skin damage. B vitamins, especially B1, B2, B3 and B5, are necessary for cellular metabolism and energy production.
Amino Acids and Related Ingredients: Amino acids, especially collagen-forming compounds proline and glycine, which are necessary for collagen production and maintaining healthy skin structures, are found in mesotherapy cocktails.

Minerals and Nucleotides: Minerals such as calcium, phosphorus and magnesium help regulate cellular functions, while nucleotides are necessary for fibroblasts' DNA and RNA synthesis.

Coenzymes and Other Antioxidants: Powerful antioxidants such as glutathione help protect skin cells by neutralizing free radicals. Coenzymes support cellular metabolism and improve fibroblast function.

Hyaluronic Acid (HA): HA, one of the most commonly used ingredients in mesotherapy cocktails, delays signs of aging by increasing the skin's moisture level. HA's water retention properties strengthen the skin barrier and increase skin elasticity.

Dimethylaminoethanol (DMAE) and Peptides: DMAE improves skin tone by increasing muscle firmness, and peptides are an important ingredient in skin rejuvenation treatments. These compounds are effective in reducing wrinkles and fine lines on the skin.

Mesoglow: This mesotherapy, used to provide brightness and uniform tone on the skin, is supported by glutathione, ascorbic acid and other skin lightening ingredients.
Mesotherapy Safety and Side Effects: Mesotherapy is generally a safe procedure. However, local reactions (bruising, redness) and rarely more serious side effects can be seen. Therefore, it is important to make a careful evaluation before mesotherapy.
Evidence and Clinical Studies: Studies on the effectiveness of mesotherapy treatments are limited, but some clinical trials have shown that formulations containing hyaluronic acid and antioxidants significantly improve skin elasticity and brightness.

Each of the ingredients used in mesotherapy cocktails has the potential to improve skin health and reduce signs of aging.

Platelet-Rich Plasma and Fibrin Treatments

Platelets are cells found in our blood and can be obtained by various processes to obtain different treatment products. These products are used in many areas other than dermatology, such as orthopedics and sports medicine. After undergoing different processes, platelets are evaluated in 4 main categories:
1. Platelet Rich Plasma (PRP): This product contains growth factors released from platelets and provides a treatment that accelerates healing. It contains many important substances, including factors that play a role in tissue healing.
2. Leukocytes and PRP (L-PRP): PRP also contains white blood cells, this version may be more effective in fighting infection.